A serial killer who wears a bunny rabbit outfit slashes his way across San Antonio before finally reaching the city's smallest rave.

　　In the tradition of UNDERWORLD and DISTRICT 9, all of Manhattan is quarantined when the Lupine virus spreads like wildfire, turning innocent civilians into ravenous wolves. Nothing short of a nuclear blast can stop the monstrous virus.

Josh Gates travels through history on a search to uncover new evidence and answers to the world's most captivating unexplained mysteries, and true stories that defy explanation, offering stunning revelations and surprising new insights.

自1985年开始，大批科学家涌向偏远的富产珍珠的卡特哈克岛，在此进行各种试验研究。直到1988年，致命流感在世界范围内蔓延，为了拯救人类，科学家们召集一群志愿者在卡特哈克岛进行转基因疫苗的试验。他们将一种寄生虫注入人类体内以增强体质，试验虽然初见成效，但大多数参与试验的人员都死于非命。

新年伊始，一个可怕的恶魔从地球几个世纪的历史中显露。当博士和她的小伙伴们回到家时，他们能否又一次战胜对地球的威胁？