- 本片是《沉默的羔羊》十周年纪念日推出的续集，这一集故事仍然改编自作家托马斯哈里斯的小说。 从高度戒备的医院逃脱的汉尼拔（安东尼·霍普金斯 Anthony Hopkins 饰）恶习难改，继续寻找他的“猎物”，不料成了曾在自己刀下侥幸活命的梅森（加里·奥德曼 Gary Ol dman 饰）的猎杀对象。梅森是一个罪大恶极的恋童癖，曾经强暴过自己的亲妹妹，年轻的时候逃狱，并且接受过人魔汉尼拔·莱克特的心理治疗，但汉尼拔·莱克特却害他半身瘫痪并且严重毁容，现在必须靠人工呼吸器维生。但是他拥有庞大的财产，并且不断收集各种不同的儿童，希望能把汉尼拔引出来，进行恐怖的报复行动。无奈之下汉尼拔求助于克莱丽斯探员（朱丽安·摩尔 Julianne Moore 饰）。两大恶魔对决，到底谁胜谁败？
- 一架从洛杉矶飞往巴黎的747航班上，搭载了几名不速之客。他们是来自美国军方的科学家，现在正计划带着一具尸体逃离美国。此前，他们在CIA的授意下对疟疾病毒进行研究，旨在开发出适合战争需要的生化武器，最终他们一种神奇的病毒应运而生。被该病毒感染的人其生命力、爆发力以及意志都空前增强，与之相对疼痛感和恐惧心理则降至最低，即使身负重伤他们也能勇往直前，决不退缩。科学家们所带的尸体正携带这种恐怖的病毒。 飞机在空中遭遇强烈的雷阵雨，剧烈的颠簸将行李舱内的尸体释放出来，并迅速化身为毫无人性、嗜血如命的恐怖僵尸。才从暴风雨的侵袭中舒缓过来的乘客们怎么也没想到，机舱很快将变成充满杀戮的血腥地狱……
- After years on the run, the mystery man known as Trick is back, but not on his own terms. Trick finds himself trapped in a cage with four other hostages - all of them paralyzed from the neck down. When Trick realizes that one of the other hostages is an old foe, Detective Epperson, the two begin working together to uncover the connection between them and their captor - a masked man they suspect is the infamous Deathstalker Killer. Meanwhile, Agent Bobby Church of the FBI is investigating Epperson's disappearance and discovers the detective vanished while he had been following a lead in the Deathstalker case. The search soon has Church crossing paths with Epperson's former partner, Scott, himself looking into the abduction of his friend, Olivia. After Scott and Church discover cellphone pictures of Olivia in the cage with both Trick and Epperson, they know they must race against the clock to find the location of the cage before time runs out, and the hostages are executed one-by-one.
- Sarah,astrugglingyoungwomanlivinginBrooklyn,agreestovolunteerasanexperimentalsubjectforapharmaceuticalcompanycalledDynamicHealthCuretobethebearerofLEXXandmakemoneytosolveherfinancialtroublesandtakecareofhermotherwhohasAlzheimer’s.Ananochipisplantedintohercerebralcortexanddesignedtotakecontrolofthebodyinordertocontaindiseasesassoonastheyoccur.Butwhentheimplantwithartificialintelligenceturnssinisterandordershertocommitcrimes,Sarahisplungedintoamurderousspiralwithonlyonechoice:toliveordie.
