警方破获神秘连环杀人案，凶手莫拉诺报复此案调查员塞尔比时，被警探科尔击中，送往研究所进行治疗。2年后，莫拉诺逃离了研究所，并要报复科尔与塞尔比。目睹亲人的死亡，塞尔比几近崩溃。当她发现莫拉诺的真实目的后，更加难以自制，并企图以死亡来求得平静……

该片故事讲述萨曼莎(瓦伦蒂娜·贝莱饰)在上学途中被一只巨型兔子绑架。15年后，在医院的她很震惊她还活着。格林博士在她身旁，试图帮助她回忆。在萨曼莎的回忆中，她被困在一个地下监狱，在那里有人强迫她玩游戏、解谜语和谜题，还有奖罚机制。同时一位命不久矣的天才前调查员也在调查这桩神秘事件。

A young woman enlists in an underground game of pain endurance in the hope of winning the million dollar prize. She soon learns the real opponent is the man who's running the game, as he employs horrific methods to manipulate and defeat her.

A hardened criminal fresh out of the joint takes a job as a handyman in a dilapidated house; but the twisted horrors he finds inside are enough to send anyone running. So why does he stay? And why are so many people drawn to Penance Lane?

January is forced to return home after six years traveling abroad. A near-fatal accident has left her temporarily wheelchair bound and depleted of her long-term memory. She is accompanied by her boyfriend 'Callum' whom she met whilst traveling. He was also the driver in the fateful accident. Not only has she forgotten her family, but her childhood as well and is surprised to discover that her home is a stately manor in the middle of the country-side. As January tries to settle in, she finds herself becoming even more estranged from her family, who just want their daughter back. The trouble is, she cannot remember who that daughter was, or why she ran away in the first place. Desperate to discover why she left all those years ago and with Callum's help, she sets out to find the truth. They soon discover the family are not as loving as they seem to be. Was there a dark reason why she left them in the first place