本片改编自真实事件，利用多线叙事的穿插，将三个时空的故事人物命运交织在一起。描述了波黑战争时期军人马尔克“意外”死亡的十二年后，伤痛依旧延绵不断地影响着每一位曾参与其中的加害者与被害者。

64年，37个美国人成为了仰望星空却不知脚下的泰勒斯，在老旧的民房中，他们专注于仰望中产阶级的梦想却听不见一个被强奸致死女性的呼声，就如和颐酒店发生的一切那般

埃琳?布罗克维奇（朱莉娅?罗伯茨 Julia Roberts 饰）是倒霉鬼中的典型。她结过两次婚，但每次婚姻都没有给她带来幸福，反而令她成了一个拖着三个孩子的单身母亲。倒霉的她在遭到一场交通事故后，连志在必得的赔偿官司到最后都输掉了。 　　为她辩护的律师埃德（阿尔伯特?芬尼 Albert Finney 饰）半是同情埃琳半是因为帮她打输了官司心感内疚，收留了埃琳在他的律师楼里打杂。埃琳的生活算是有了一点保障。在调查一单污水申诉案时，埃琳偶然发现了污水中含剧毒物质，而供水公司确对此敷衍了事。弱女子埃琳决定用她柔弱的肩膀担负起为受污染的数百名居民讨回公道的重担！

丹尼?达可（杰克?盖伦霍尔 饰）患有精神疾病，某天晚  上他受到莫名的召唤，梦游，也因此逃避了一架飞机坠落在他房间天花板上，这样匪夷所思的事故。　　自此以后，他的生活就发生了变化，频频出现幻觉，他时常看见一个兔人弗兰克，后者告诉他世界将在28天6小时48分12秒以后毁灭；他得到了一本书，《时空旅行奥义书》，对书中提到的时空旅行、离线宇宙产生了强烈的好奇。　　随着世界末日的临近，杰克的生活越来约诡异，他新认识的女朋友和家人也被卷了进去。看来，杰克想实现拯救世界的愿望，需要付出更多的代价。

In a complex tale of interweaving relationships, a Greek immigrant in London explores the meaning of what it is to love and heal. Poised follows the story of Aris, a gay Occupational Therapist who carries the weight of a previous relationship gone wrong. Yet, a chance encounter with Richard seems to allow him the chance to love again. As Aris' relationship with Richard deepens, so too does his friendship with Anna, a patient in his care who suffers from a rare neurological syndrome that leaves her paralysed. Anna recovers the use of her limbs, but finds that she has come to rely on Aris for much more than just his support. In fact, her discovery that her husband has been unfaithful during her illness triggers the realisation that her feelings for Aris are romantic. The ties that bind emotion and propriety begin to unravel, and the tangled net that is woven will hold a secret that will catch them all.